THE IMPORTANCE OF BLOOD CULTURES IN THE DIAGNOSTIC AND THERAPEUTIC PROCESS OF SEPTICEMIA
- Project Research
- 1-5 Chapters
- Abstract : Available
- Table of Content: Available
- Reference Style: APA
- Recommended for : Student Researchers
- NGN 3000
ABSTRACT
A study of septicaemia was conducted in Enugu metropolis with a view to determine the relevance of blood culture to the diagnosis and treatment of this disease. The subjects comprised of Six hundred and fifty (650) children and adults of both sexes aged between one day to 70 years having clinical features suggestive of septicaemia, who were on admission at University Of Nigeria Teaching Hospitals (UNTH), Enugu. Their blood specimens were seeded into thioglycolateand glucose broths and incubated at 37 °C for 7 days. Subcultures were performed after 1, 2, 3, 4 and 7 days respectively. Growth (positivity) in the broths was assessed using conventional diagnostic methods namely macroscopy(visualization), Gram filming (microscopy) and culture. The bacterial isolates harvested were subjected to in-vitroantibiotic susceptibility tests using the disc diffusion method. Etiology was established in 104 out of 350 subjects indicating an incidence of 29.7%.
This difference in prevalence among different age groups was statistically significant(P < 0.01). The males (59/350, 16.86%) appeared to be more susceptible to septicaemia than the females (45/350, 12.9%) in all the age groups.
This variation had no statistical significance (P > 0.01). Monomicrobialsepticaemia had ahigher prevalence (91.3%) than polymicrobialsepticaemia (8.65%). Staphylococcus aureusand Escherichia coliconstituted 33.3%. Most of the offensive microbes were facultative anaerobes (93.3%) while very few were strict aerobes (7.69%) and strict anaerobes (1.92%). The isolated anaerobes were Peptostreptococcussp. (1%) and Bacteroidesfragilis(1%). The in vitro susceptibility of the bacterial isolates to antibiotics indicated 78.9-92.9% sensitivity to vancomycin, zinnat, peflacin and fortum. However, they were 60 – 90% resistant to penicillin, ampicillin, tetracycline and septrin. This study confirmed the diverse nature of bacterial etiologies of septicaemia in Enugu metropolis; the need for the use ofthioglycolate broths, first subcultures on or before 24 h instead of starting off for after 48 h of incubation, complementary application of macroscopy, Gram filming and culture including antibiotic susceptibility test as an integral part of diagnosis and treatment of septicaemia is hereby advocated, most especially in the developing countries of the world.
Related Project Materials
THE EFFECTS OF OIL SPILLAGE IN THE NIGER DELTA A CASE STUDY OF UGHELLI SOUTH LOCAL GOVERNMENT AREA OF DELTA STATE
ABSTRACT
The research work aimed at finding the effect of oil spillage in the Niger Delta, the causes o...
ASSESSMENT OF THE LEVEL OF COMPLIANCE TO HEALTH AND SAFETY MANAGEMENT SYSTEM BY CONSTRUCTION FIRMS IN OWERRI IMO STATE
ABSTRACT
This study was carried out to evaluate the level of compliance to health and safety management...
PARASITOLOGICAL EXAMINATION OF SOME READY TO EAT FRUITS SOLD AT OYE EMENE ENUGU STATE NIGERIA
ABSTRACT
Some locally available fruits (garden egg, orange, banana, guava, avocado, pawpaw and pineapple).sold in Oye Emene Enugu, Enugu...
THE ROLE OF ACCOUNTING FOR INTERNATIONAL JOINT VENTURES AND ALLIANCES
THE ROLE OF ACCOUNTING FOR INTERNATIONAL JOINT VENTURES AND ALLIANCES
ABSTRACT
This research aims to examine (1) the role...
A SURVEY OF THE EXTENT AND TYPE OF INSTRUCTIONAL MATERIAL IMPROVISATION IN SECONDARY SCHOOL
ABSTRACT
This study examined the Effects of Improvised instructional materials on the academic performance of junior se...
ASSESSMENT OF GLOBAL FOOD INSECURITY AS A THREAT TO NATIONAL DEVELOPMENT (A CASE STUDY OF NIGERIA 2016 TO 2021)
Background of the Study
For many centuries, the concept of food security was understood to mean the capability of a nati...
ASSESSMENT OF PASSIVE SECURITY MEASURES IN THE DESIGN OF A HOTEL IN MINNA, NIGER STATE
ABSTRACT
Security and safety are important factors to be considered in every design. This has in recent times become an issue of concern...
THE IMPACT OF EARLY CHILDHOOD EDUCATORS IN PROMOTING MULTICULTURAL UNDERSTANDING AND DIVERSITY APPRECIATION AMONG YOUNG CHILDREN
Abstract: This study examines the role of early childhood educators in promoting multicultural understanding and...
EFFECTS OF LIBRARY INSTRUCTIONS ON THE USE OF INFORMATION RETRIEVAL TOOLS BY STUDENTS IN POLYTECHNIC LIBRARIES
Abstract
Instructing library users on effective utilization of information resources and services could not be over emphasized in tertiar...
STATISTICAL ANALYSIS OF ROAD ACCIDENTS (A CASE IN ENUGU STATE FROM 1993 TO 2000)
BACKGROUND OF THE STUDY
In the world today, transportation which is the conveyance of goods and passeng...
